Bagian Farmakologi

Ketua dan Anggota Bagian Farmakologi

  • Retnosari Andrajati, MS., Ph.D., Apt. (Ketua)
  • Dra. Juheini A., M.Si., Apt.
  • Santi Purna Sari, M.Si., Apt.
  • Anton Bachtiar, M.Si., Ph.D., Apt.
  • Fadlina Chany S., M.Si., Ph.D., Apt.
  • Nadia Farhanah Syafhan, M.Si., Apt.

 

Bagian farmakologi melakukan kegiatan yang antara lain terdiri dari :

  1. Melakukan uji praklinik dan toksisitas obat-obat modern, obat tradisional, senyawa bahan alam dan zat kimia hasil sintesa lainnya.
  2. Uji farmakodinami dan farmakokinetik terhadap obat-obat kardiovaskuler, analgesik-antiinflamasi, antidiabetik oral, antihiperlipidemia, dan antihiperkolesterolemia.
  3. Penelitian toksisitas akut dan sub-kronis sediaan farmasi.
  4. Uji parameter farmakokinetika obat untuk menentukan bioavailabilitas/ ketersediaan hayati obat.
  5. Uji parameter biofarmasetik untuk menentukan absorpsi dan distribusi obat.
  6. Uji monitoring efek terapi penggunaan obat pada pasien.

Topik Penelitian :

  1. Efek Daun Salam pada sistem Kardiovaskuler tikus.
  2. Uji antihipertensi dan hiperkolesterolemia ekstrak daun dewa
  3. Uji efek analgesik dan antipiretik ekstrak daun kemuning
  4. Uji antidiabetik beberapa jenis jamur
  5. Bioavailabilitas relatif kapsul Tetrasiklin generic
  6. Bioavailabilitas relatif tablet karbamazepin generic

Beberapa Publikasi :

  1. Joshita Djajadisastra1, Alice Laznickova1, Helmut R.Macke2,Binding of111In-DTPA-Octreotide, of111In-DOTA-Octreotide and 88Y-DOTA-TYR-Octreotide to plasma proteins,Folia Pharm. Univ.Carol. 26, 2001, 89-92.
  2. Joshita Djajadisastra1, Alice Laznickova1, Josef Dolejs1,Effect of Temperature on the Binding of Benzoate by Human Serum Albumin.MAKARA, Jurnal Penelitian Universitas Indonesia, Vol.I, No.9, Seri Sains, Juni 2001, hlm. 29-37.
  3. Joshita Djajadisastra1, Alice Laznickova1, Josef Dolejs1.The Binding of Benzoate by Human Serum Albumin and its Temperature Dependence. Ceskoslovenska Fyziologie 2000, Cislo 4, Rocnik 49:166.
  4. Josef Dolejs, Joshita Djajadisastra.Postnatal Mortality from Meningococcal Infections during the period 1950-1991 in US.Mechanisms of Ageing and Development, 2000, 119:9-13.
  5. Joshita Djajadisastra1, Alice Laznickova1,The Binding of Radiolabelled Receptor-Specific Peptide to Plasma Proteins,Pan Pacific X Conference, 23-25 June 2003, Bali, Indonesia, 2003.
  6. Prasetyowati Subchan (FK Undip), Retno I.S.Tranggono (Ristra Indolab), Joshita Djajadisastra (FMIPA UI).The Influence of Soy Isoflavon to the Skin Aging in Pre Menopausal Women. 2003 IFSCC Conference, September 22-24, 2003 Seoul, Korea.
  7. E.I. Ilyas, A. Bahtiar, A.Estuningtyas, C.Vitasyana, B.M.Nur, M.Siagian,dkk.Curcuminoids in Cardiac ischemia/Hypoxia and Reperfusion/Reoxygenation in Isolated Working Guinea Pig Hearts. 2ndInternational Symposium on Antioxidantss in Nutrition & Therapy., Bali – Indonesia, October 2 – 4, 2002.
  8. Bahtiar A., Ilyas E.I, Suyatna FD, Setyawati A, tadjudin MK, H-J Freisleben.Curcumin Could Repair Haemodynamic and Biochemistry Aspect in 60 Minutes of Hypoxia and 30 Minute of Reoxygenation Isolated Working HeartGuinea Pig. 2ndInternational Symposium on Antioxidantss in Nutrition & Therapy., Bali – Indonesia, October 2 – 4, 2002.
  9. Estuningtyas A, Suyatna FD, Istiantoro Y, Ilyas E, Bahtiar A.The Effect ofCurcumin Toward Glutathione Content and Glutathione Reductase Activity in Hypoxia/Reoxygenation Isolated Working Heart Guinea Pig Mitochondria. 2ndInternational Symposium on Antioxidantss in Nutrition & Therapy., Bali – Indonesia, October 2 – 4, 2002.
  10. Vitasyana C, Bahtiar A, Suyatna FD, Setiawati A, Ilyas E, Tadjudin MK, H-J Freisleben.The Effect of Curcumin Toward Glutathione Peroxidase Activity in Hypoxia/Reoxygenation Isolated Guinea Pig Mitochondria. 2ndInternational Symposium on Antioxidantss in Nutrition & Therapy., Bali – Indonesia, October 2 – 4, 2002.